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Siberian Ginseng – Identification of medicinal uses, interactions, side effects,

Siberian Ginseng

Eleutherococcus senticosus (syn. Acanthopanax senticosus) is in the same botanical family as ginseng (Araliaceae), but is not a member of the genus Panax it is not considered a true ginseng. E. senticosus, also known as Eleuthero, is commonly known as Siberian or Russian ginseng because it is from the east Russia. The root or root bark is used medicinally.

Uses and Benefits:

Siberian Ginseng is said to have powerful adaptogenic and tonic properties that can modulate stress and improve physical and mental health in a variety of stress conditions. It was discovered by scientists Soviets were looking for an alternative to Asian ginseng and other adaptogenic herbs. Officially approved for use in Russia in 1962, Siberian Ginseng has become in a popular beverage business to help improve endurance. In traditional Chinese medicine, this plant is considered a minor tonic (called Wu Jia below). It has been used for bronchitis, digestion, heart disease, rheumatism, headaches and insomnia, and in general restore vigor and health.

Pharmacology:

Eleuthero (AG) is considered the most important components in the roots of Siberian ginseng. Unlike gender ginsenosides Panax, however, the eleutherosides are a diverse group of chemicals from chemical plants (Iignans, sterols, phenylpropanoids, coumarins, etc.), not are unique to E. senticosus. Soviet scientists conducted experiments with many animals, Siberian ginseng, and reported improvement in resistance physical and resistance to infection, radiation, cancer, toxins, and the variety of extreme environmental conditions II. Anabolic steroids, estrogens, other anliviral effects, hypotension, and many have also been shown in animal models. Conflicting reports in which extracts induced hypoglycemia and hyperglycemia in animals or to improve not only sedation and central nervous system stimulation is explained by the "adaptogen" properties of the plant. Alternatively, can be explained by different extracts or experimental conditions. Most previous studies of the resistance of the animals are raised, which also raises the question researcher bias, a more recent study was blinded negative.

pharmacological data in humans are limited. It would be a double-blind, controlled placebo, 10 ml three times daily for four weeks a German product significantly increased the cell about 50% in 36 healthy volunteers. In a non-blinded, randomized controlled, 25 drops three times daily of an extract of the roots of ethanol decreased glucose and cholesterol (total, LOL, and triglycerides) and increased activity neutrophils and lymphocytes in 50 healthy volunteers.

Clinical trials:

Most of the original trials Russia were reviewed and summarized. Initial investigations indicated that better athletes, and athletes had a higher endurance and concentration, and workers have fewer sick days when taking Siberian ginseng. In many studies involving more than 2,100 healthy subjects, Siberian ginseng has been reported to demonstrate the effects adaptogens to help resist the various items in adverse conditions and stressors (workload, noise, movement, heat, etc.) resulting in higher performance at work. Studies in over 2200 patients reported unhealthy "benefits" of various diseases such as atherosclerosis and heart disease, acute pyelonephritis, diabetes, chronic bronchitis, hypertension and hypotension, trauma, neurosis, and cancer. However, measurements of actual results the clinical benefits are not well defined. Furthermore, these studies were uncontrolled or unblinded, and do not meet current standards for clinical research high quality.

In more recent controlled trials, the benefits for endurance sports reported for the first time in a single blind, controlled placebo, and showed improvements in muscle strength in a placebo-controlled trial, blinding light. A Chinese study also reported an increase in anaerobic threshold electrical charge has diminished emd respiratory quotient (suggesting greater fat metabolism ism during exercise). However, the double-blind study stringent could not verify these potential benefits. A series of small controlled trials ergometer or bicycle tape found no ergonomic benefits Siberian ginseng brand called Endurox. Another well-designed trials of 20 runners did not find the ergonomic advantages ethanol extract administered eleutherosides Band E daily for 6 weeks compared with placebo. A well-designed randomized, crossover, double-blind study found no measurable benefit in nine ergonomic or metabolic cyclists, with placebo were randomized to receive either 1200 mg of Siberian ginseng daily for 7 days before the two endurance cycling.

The Side effects:

Siberian ginseng is considered safe and nontoxic, although data are limited. No side effects were observed in a recent essay of man, and no well-documented case report of adverse effects. In studies of Russian origin, adverse reactions have been reported in healthy subjects, but it was suggested that ginseng Siberian should not be used when blood pressure above 180/90. In "unhealthy" patients, the reactions of insomnia, arrhythmias, hypertension, pain headache, irritability and anxiety were reported frequently. Caution is therefore recommended for patients with disease of heart disease, hypertension, psychiatric disorders or the use of caffeine or other stimulants, even if these side effects are not well established.

Side effects and interactions:

In two separate cases, adulterated or misbranded Eleutherococcus preparations (probably Periploca sepium, which contains glycosides heart) were associated with androgenization in a newborn with absent increased digoxin toxicity. Siberian ginseng safety is unknown in women who are pregnant or breastfeeding.

Preparations and dosages:

Several products are in the U.S. market preparations of the dried herb to a variety extracts. In studies of Russian origin, the doses were generally taken for a maximum of 4-8 weeks at a time, interrupted by 2-3 weeks of ginseng-free intervals, but not no data to support these programs. Common dose extracts encapsulated in the market today include one to three capsules of 100 to 400 mg 2-3 times a day, more or less equivalent to 1-4 g / day or a product over a dried root.

Assessment Summary:

Siberian Ginseng is commonly used as an adaptogen to help modulate the response to stressors and improve mental and physical endurance and stamina. These statements are based largely on studies in animals and early clinical investigations by Soviet scientists. Siberian Ginseng improves physical strength is not based on clinical trials more recent. Limited studies suggest that Siberian ginseng can increase leukocyte activity, patients with lower cholesterol and glucose, improves memory, and has herpes infections at a face, but these studies require confirmation and, in general, the effectiveness of Siberian ginseng has not been established beyond reasonable doubt for any indication. Based on limited data, Siberian Ginseng appears safe with no side effects documented.

About the Author

Steve Mathew is a writer, who writes many great articles on herbal medicines for common ailments and diseases. For more information on herbal remedies and home remedies visit our site on health care.

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